2 edition of Synthetic Polypeptides As Antigens (Laboratory Techniques in Biochemistry and Molecular Biology) found in the catalog.
Synthetic Polypeptides As Antigens (Laboratory Techniques in Biochemistry and Molecular Biology)
M. H. V. Van Regenmortel
by Elsevier Science Publishing Company
Written in English
|The Physical Object|
|Number of Pages||350|
Characteristics of Antigens• Chemical nature of antigens: – proteins – polysaccharides – lipopolysaccharides – nucleoproteins – glycoproteins – steroid hormones – bacterial cells, viruses – synthetic polypeptides – synthetic polymers1/5/ MD 4 5. b. Penicillin, for example, a clinically important hapten, has a molecular weight of Daltons ( kDa). 3. if a hapten of coupled to a larger carrier molecule, however, it becomes endowed with immunogenicity. a. The carrier molecules may be albumins, globulins, or synthetic polypeptides. b.
Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology. Those using synthetic peptides as immunological probes will find this a most useful book, as will those wishing to overcome the difficulties of achieving antigenic mimicry by. EPB1 EPA EPA EPB1 EP B1 EP B1 EP B1 EP A EP A EP A EP A EP A EP A EP B1 EP B1 EP B1 Authority EP European Patent Office Prior art keywords polypeptide ea amino acid antibodies immunoreactant Prior art date Legal .
Laboratyory Techniques in Biochemistry and Molecular Biology Synthetic Polypeptides As Antigens by S. Muller, J. P. Briand Published ISBN , ISBN: Synthetic polypeptides have the advantage of being composed of much simpler components than natural proteins, but do not present the complex biological activity of a protein. However, due to their 3D structure and biocompatibility, polypeptides have become the most promising materials in many bio-applications, such as drug and gene delivery.
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Synthetic Polypeptides As Antigens (Laboratory Techniques in Biochemistry & Molecular Biology) (v. 19) by M. Van Regenmortel (Author), J. Synthetic Polypeptides As Antigens book Briand (Author), S.
Muller (Author), S. Plaue (Author) & 1 more ISBN Cited by: Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays.
This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic Book Edition: 1. Synthetic Polypeptides as Antigens Edited by R.H. Burdon, P.H. van Knippenberg Vol Pages ii-xv, ().
Summary: Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their.
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Studies on synthetic polypeptide antigens. The role of composition, charge, and optical isomerism in the immunogenicity of synthetic polypeptides. polypeptides composed of glutamic acid, lysine, and tyrosine (2, 3) showed that tyrosine was the most potent antigenic deter- minant, lysine was quite potent, and glutamic acid was only moderately.
Purchase Antigens, Lymphoid Cells and the Immune Response - 1st Edition. Print Book & E-Book. ISBNSynthetic Polypeptides-The polypeptides were synthesized by polymerization of the N-carboxyanhydrides in a 1 y.
solution in benzene or in 95 y. benzene and 5 y. nitrobenzene with the use of sodium methoxide as the initiator at an anhydride to initiator ratio of Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides (NCAs) are one of the most important unique features of these synthetic polypeptides, including their chemical diversity of side chains and their ability to form secondary structures, enable their broad applications in the field of gene delivery, drug delivery, bio-imaging, tissue engineering.
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that have found broad biomedical applications. Ring-opening polymerization of N-carboxyanhydrides offers a reliable way to prepare high-molecular-weight polypeptides in large scale with diverse side-chain functionalities.
The past two decades have seen significant advances in the polypeptide field. Synthetic Polypeptides As Antigens (Laboratory Techniques in Biochemistry and Molecular Biology) DecemberElsevier Science Publishing Company Hardcover in English.
In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic.
Janeway, C. Jr., Sela, M.: Synthetic antigens composed exclusively of L- or D-amino acids. Effect of optical configuration on the immunogenicity of synthetic polypeptides in mice. Immunol 29–38 (). PubMed Google Scholar. Synthetic peptide vaccines Most existing vaccines are prepared from an attenuated version of the pathogen or from inactivated disease-causing organisms or a suitable part of it e.g.
a toxin. However, often the antigen to which the immune system responds is a. Antigens, immunogens, inocula, antibodies, diagnostic methods and systems relating to Epstein-Barr virus nuclear antigen (EBNA) are disclosed.
Each of the compounds, compositions, methods or systems contains a synthetic, random copolymer polypeptide having about 6 to about 40 residues, or an antibody containing site that immunoreacts with such. Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology.
Those using synthetic peptides. Synthetic polypeptides from the ring-opening polymn. of N-carboxyanhydrides (NCAs) are one of the most important biomaterials.
The unique features of these synthetic polypeptides, including their chem. diversity of side chains and their ability to form secondary structures, enable their broad applications in the field of gene delivery, drug. A synthetic vaccine is a vaccine consisting mainly of synthetic peptides, carbohydrates, or antigens.
They are usually considered to be safer than vaccines from bacterial cultures. Creating vaccines synthetically has the ability to increase the speed of production.
This. Much effort has been put into the study of synthetic antigens. The literature is so extensive that no attempt is made to cover it, even in a superficial way.
Maurer (), Sela (), and Schlossman () have written articles to which readers are referred. A very large number of synthetic polypeptides has been described. In the last two decades, many new peptides have been developed, and new knowledge on how peptides improve the skin has been uncovered.
The spectrum of peptides in the field of cosmetics is continuously growing. This review summarizes some of the effective data on cosmeceutical peptides that work against intrinsic and extrinsic aging.
Some peptides have been proven in their efficacy through.SJL mice are high responders to the synthetic multichain polypeptide antigen (T,G)-Pro--L, whereas DBA/1 mice are low responders (10, 11).
In order to determine whether the genetic control of immune response can be correlated with the number of antigen-sensitive precursor cells, spleen cell suspensions from normal and immunized SJL and DBA/1 donor mice were transplanted into lethally X.The present invention relates to polypeptides of Streptococcus pneumoniae which may be used for prophylaxis, diagnostic and/or therapy purposes.
USB2 - Streptococcus antigens - Google Patents Streptococcus antigens Download PDF Info Publication number USB2. USB2.